An Online Solid Phase Extraction-Liquid Chromatography Tandem Mass Spectrometry Method for the Analysis of Parabens in Urban Waters

In this work, we report a method to quantify methylparaben, ethylparaben, propylparaben and butylparaben in urban waters of São Carlos (São Paulo State, Brazil) by online solid phase extraction-liquid chromatography tandem mass spectrometry (SPE-LC-MS/MS) system. The achieved ng L-1 limits with good accuracy precision (internal standards for each paraben were used). total run cycle time takes 9.5 min per sample including the extraction, cleanup columns conditioning cycles, lower collection volumes water solvent usage. SPE cartridge applied showed robustness allowing over 500 injections (800 μL each) chromatographic performance. This study findings included detection parabens samples Carlos.